Left ventricular global function index and peculiarities of daily blood pressure profile in patients with arterial hypertension

BACKGROUND: The left ventricular global function index (LVGFI), determined using transthoracic echocardiography, is a simple clinical marker of dysfunction and has superior prognostic value to the standard ejection fraction-based assessment cardiac pump function. methodology for calculating this was proposed in 2019. Currently, factors that influence state functions are not examined.
 AIM: This study aimed assess association LVGFI with peculiarities daily blood pressure (BP) profile patients arterial hypertension (AH).
 MATERIALS AND METHODS: A total 104 [51 men (49%) 53 (51%) women] AH were examined. mean age 58.711.73 years, disease duration 6.0310.93 years. corresponded grades 1, 2, 3 47 (45.2%), 26 (25.0%), 31 (29.8%) patients, respectively. Patients myocardial infarction or stroke, cardiomyopathies, heart defects, diabetes mellitus, thyroid dysfunction, chronic kidney included study. All underwent BP monitoring, carotid artery examination, biochemical tests.
 RESULTS: significant inverse weak correlation (r=0.215, p=0.028), body mass (r=0.378, p=0.001), variability (r=0.307, p=0.002), values systolic (r=0.223, p=0.026) diastolic (r=0.237, p=0.018) observed. In regression analysis, an increase index, abnormal diurnal excessive reduction at night, high demonstrated independent decreased LVGFI.
 CONCLUSIONS: revealed increased variability. These should be considered possible development strategy prevent target organ damage AH.